Well, you know that Dean Cain signed on to play for the Buffalo Bills when he got out of college, right? But then he blew out his knee and couldn't play again? Well, I just watched 'And the Answer Is...', and when Clark is talking to that florist (trying to track down Mazik from the scent), this is the dialouge:

Clark: You played for the Buffalo Bills, right?
Florist: Yeah, 'till I blew out my knee.
*some snippets of dialouge later*
Clark: Yeah, I know all about that.

laugh I just found that funny and ironic.